Chronic wounds become "stalled" in the inflammatory phase of wound healing due to an increased development of proteolytic enzymes with degradation of the extracellular matrix (ECM). Wound chronicity is a hyperinflammatory and proteolytic state that impedes healing. For many years, the scientific community has identified collagen as the common element and denominator in the body's natural healing response.
Collagen helps the body heal itself by preparing the wound bed, balancing wound chemistry, causing cell migration and growth, inducing granulation tissue, and improving overall skin strength. Collagen's role in these various chemicals, mechanical and biological factors, forms an environment conducive to wound healing, and ultimately, to wound closure.
Cleanses the wound
Establishes new tissue and blood vessels
Creates structural matrix
Closes the wound
Regains original integrity
Wounds should follow the same healing response, but factors such as clinical conditions and complications may alter or halt the ideal healing process. In these cases, collagen-related activity redirects the wound to the normal healing path.