Medifil® II

Medifil® II Collagen Particles are bovine collagen fibers bio-engineered for advanced wound care applications using our proprietary Kollagen™ technology.

Medifil® II Collagen Particles (vials and pouches available)


  • Easily applied to any size wound and in hard to reach areas.
  • Absorbs 40-60 times its weight in fluid
  • Maintains an optimal moist wound-healing environment
  • Promote angiogenesis - new tissue growth supporting wound healing
  • Chemically binds and decreases matrix metalloproteinases (MMPs) found in the extracellular fluid.
  • For non-infected and infected wounds
  • Compatible with topical agents and other dressings


SizeHCPCS* Code
1 Gram Vial MF2001
1 gram pouch MF2002

*Products are reimbursable in the USA.


Dressing wear time should be based on the condition of the wound and clinical assessment. Always consult a physician for changes in wound condition and treatment plan monitoring and follow up.

  1. Cleanse wound as per physician order: preferably normal saline or non-cytotoxic wound cleanser or wash.
  2. Line wound bed with Medifil ®  II collagen particles up to 1/4 inch depth.
  3. Cover wound with a secondary dressing: e.g. transparent, gauze, abdominal pad, foam, super absorbent pad, hydrocolloid to promote thermoregulation and enhance wound healing.
  4. Daily dressing change

Indications: Acute and Chronic Wounds

Partial-thickness wounds – Loss involving epidermis, dermis, or both. Shallow open ulcer. Red/pink wound bed, without slough or eschar.

  1. Arterial ulcers
  2. Venous ulcers
  3. Diabetic Neuropathic ulcers
  4. Pressure Injury Stage 2
  5. Blisters
  6. Second-degree burns
  7. Superficial abrasions

Full thickness wounds- Loss of epidermis, dermis, into subcutaneous tissue or extending to muscle, tendon, and bone. Subcutaneous fat may or may not be visible. Slough and or eschar may or may not be present. *Collagen can be used in wounds with scattered slough or eschar.

  1. Arterial ulcers
  2. Venous ulcers
  3. Diabetic Neuropathic ulcers
  4. Pressure Injury Stage 3, 4
  5. Donor sites
  6. Dehisced surgical wounds
  7. Traumatic wounds healing by secondary intention


  • Do not use on third-degree (full thickness) burns
  • Do not use in patients with collagen or bovine sensitivities